Researchers have used high-density nanofibers that mimic the microenvironment of the brain to capture tumor cells, opening doors to novel therapeutic solutions for aggressive brain cancer.
Researchers have discovered a new way to jump-start the immune system to attack tumors, which could allow cancer immunotherapy to be used against more types of cancer.
Men who inherit an increased risk of cancer through ‚Lynch syndrome‘ could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Annual PSA tests were eight times more likely to spot cancer in men with genetic hallmarks of Lynch syndrome than those without. Experts say evidence could be incorporated into a targeted screening program in future.
Researchers have made recommendations for clinicians and patients regarding supplemental screening for women with dense breast tissue.
Researchers describe a new liquid biopsy method using lab-on-a-chip technology that they believe can detect cancer before a tumor is even formed. Using magnetic particles coated in a specially designed bonding agent, the liquid biopsy chip attracts and captures particles containing cancer-causing biomarkers. A close analysis can identify the type of cancer they are carrying. This, the researchers say, can significantly improve cancer diagnosis and treatment.
Researchers fabricate gold nanoparticles with a rapidly decaying radioisotope that can be internalized by cancer cells. Because the radiation remains strongly localized, high doses can be administered without concern for side effects. This research may lead to safer and more effective treatments for many types of cancer.
If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later according to recent analyses.
Researchers have identified a chemical compound that may be suitable as an active agent against several different unicellular parasites. Among these are the pathogens that cause malaria and toxoplasmosis. The point of attack for this promising substance is the protein tubulin: It helps cells divide and therefore is essential for the multiplication of the parasites.
Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms. By deciphering the cell migration mechanisms underlying the immune response, scientists have shown that the activation of the immune system is modulated according to the time of day. Indeed, the migration of immune cells from the skin to the lymph nodes oscillates over a 24-hours period. Immune function is highest in the resting phase, just before activity resumes — in the afternoon for mice, which are nocturnal animals, and early morning for humans. These results suggest that the time of day should possibly be taken into account when administering vaccines or immunotherapies against cancer, in order to increase their effectiveness.
Scientists have discovered a new link that could bring the scientific and medical community closer to understanding why glioblastoma, the most common malignant brain tumor, is deadlier in males than females.
A new study examines how the extracellular matrix (ECM) — an underlying network of molecules and proteins that provide the structure for tissue growth — can trigger invasive cancer-related genes.
Molecular atlas of small cell lung cancer reveals unusual cell type that could explain why it’s so aggressive
Stem-like cells that make up only a tiny fraction of the total cells in a lung tumor could be the key to stopping the disease’s deadly spread, say researchers.
Researchers have discovered how T cells — an important component of our immune system — are able keep on killing as they hunt down and kill cancer cells, repeatedly reloading their toxic weapons.
Data continues to show that American’s need at least 5 hours per week of physical activity to prevent some cancers
A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines.
For nearly a decade, scientists have known that HIV integrates itself into genes in cells that have the potential to cause cancer. And when this happens in animals with other retroviruses, those animals often develop cancer. But, perplexingly and fortunately, that isn’t regularly happening in people living with HIV. A new study reveals why doctors aren’t seeing high rates of T cell lymphomas — or cancers of the immune system — in patients with HIV.
The prognosis for a cancer patient who undergoes surgery is better if the surgeon removes all of the tumor, but it can be hard to tell where a tumor ends and healthy tissue begins. Now, scientists report that they have developed a fluorescent spray that specifically lights up cancerous tissue so it can be identified readily and removed during surgery.
Scientists have discovered a highly potent monoclonal antibody that targets the SARS-CoV-2 spike protein and is effective at neutralizing all variants of concern identified to date, including the delta variant.
A researcher has discovered an enzyme that plays a key role in the ability of cancer cells to resist drug treatment.
Mushrooms have been making headlines due to their many health advantages. Not only do they lower one’s risk of cancer and premature death, but new research also reveals that these super-foods may benefit a person’s mental health.
Scientists have developed a chemical compound that interferes with a key feature of many viruses that allows the viruses to invade human cells. The compound, called MM3122, was studied in cells and mice and holds promise as a new way to prevent infection or reduce the severity of COVID-19 if given early in the course of an infection, according to the researchers.
New research finds many women are screened too often for cervical cancer, leading to unnecessary procedures that may carry their own harms, while some women are not getting tested often enough, putting them at higher risk for poor outcomes.
The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called ‚don’t eat me‘ signal, which tells the immune cells to stand back. Tumor cells exploit this CD47-based protection strategy for evading the immune system, by increasing presentation of CD47 on their cell surface. A team has now developed a therapy concept for programming the tumor cells to produce on their own a CD47-blocking and immune-activation fusion protein. This therapy approach could stop tumor growth.
Common gut bacteria can become ‚hormone factories‘ – fuelling prostate cancer and making it resistant to treatment, a new study shows. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy — by providing an alternative source of growth-promoting androgens, or male hormones. The findings, once further validated in the clinic, could provide new opportunities for the treatment of prostate cancer through manipulation of the microbiome.
Researchers have shown for the first time how mutations affecting a cellular process called RNA splicing alter cells to develop myelodysplastic syndrome (MDS) and other hematologic malignancies and solid tumors.