New cancer treatment may reawaken the immune system

Researchers have discovered a new way to jump-start the immune system to attack tumors, which could allow cancer immunotherapy to be used against more types of cancer.

Quelle: Sciencedaily

Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Men who inherit an increased risk of cancer through ‚Lynch syndrome‘ could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Annual PSA tests were eight times more likely to spot cancer in men with genetic hallmarks of Lynch syndrome than those without. Experts say evidence could be incorporated into a targeted screening program in future.

Quelle: Sciencedaily

Guidance on supplemental breast cancer screening for women with dense breast tissue

Researchers have made recommendations for clinicians and patients regarding supplemental screening for women with dense breast tissue.

Quelle: Sciencedaily

New way to find cancer at the nanometer scale

Researchers describe a new liquid biopsy method using lab-on-a-chip technology that they believe can detect cancer before a tumor is even formed. Using magnetic particles coated in a specially designed bonding agent, the liquid biopsy chip attracts and captures particles containing cancer-causing biomarkers. A close analysis can identify the type of cancer they are carrying. This, the researchers say, can significantly improve cancer diagnosis and treatment.

Quelle: Sciencedaily

Targeting cancer at the nanoscale

Researchers fabricate gold nanoparticles with a rapidly decaying radioisotope that can be internalized by cancer cells. Because the radiation remains strongly localized, high doses can be administered without concern for side effects. This research may lead to safer and more effective treatments for many types of cancer.

Quelle: Sciencedaily

Starting mammography at age 40 would reduce disparities in deaths for Black women

If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later according to recent analyses.

Quelle: Sciencedaily

Molecular atlas of small cell lung cancer reveals unusual cell type that could explain why it’s so aggressive

Stem-like cells that make up only a tiny fraction of the total cells in a lung tumor could be the key to stopping the disease’s deadly spread, say researchers.

Quelle: Sciencedaily

Mito warriors: Scientists discover how T cell assassins reload their weapons to kill and kill again

Researchers have discovered how T cells — an important component of our immune system — are able keep on killing as they hunt down and kill cancer cells, repeatedly reloading their toxic weapons.

Quelle: Sciencedaily

Data continues to show that American’s need at least 5 hours per week of physical activity to prevent some cancers

A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines.

Quelle: Sciencedaily

Fluorescent spray lights up tumors for easy detection during surgery

The prognosis for a cancer patient who undergoes surgery is better if the surgeon removes all of the tumor, but it can be hard to tell where a tumor ends and healthy tissue begins. Now, scientists report that they have developed a fluorescent spray that specifically lights up cancerous tissue so it can be identified readily and removed during surgery.

Quelle: Sciencedaily

Researcher discovers key gene responsible for cancer drug resistance

A researcher has discovered an enzyme that plays a key role in the ability of cancer cells to resist drug treatment.

Quelle: Sciencedaily

Mushroom consumption may lower risk of depression

Mushrooms have been making headlines due to their many health advantages. Not only do they lower one’s risk of cancer and premature death, but new research also reveals that these super-foods may benefit a person’s mental health.

Quelle: Sciencedaily

Aadvance in rapid cancer detection and monitoring

An engineer is reporting fast screening of the surface proteins of exosomes for cancer diagnostics and biomarker discovery.

Quelle: Sciencedaily

Researchers find cervical cancer screening is overused – and underused as well

New research finds many women are screened too often for cervical cancer, leading to unnecessary procedures that may carry their own harms, while some women are not getting tested often enough, putting them at higher risk for poor outcomes.

Quelle: Sciencedaily

‘Gut bugs’ can drive prostate cancer growth and treatment resistance

Common gut bacteria can become ‚hormone factories‘ – fuelling prostate cancer and making it resistant to treatment, a new study shows. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy — by providing an alternative source of growth-promoting androgens, or male hormones. The findings, once further validated in the clinic, could provide new opportunities for the treatment of prostate cancer through manipulation of the microbiome.

Quelle: Sciencedaily

Small molecule may prevent metastasis in colorectal cancer

The compound works by hindering a key pathway that cancer cells rely upon to hoard energy, and is already undergoing clinical trials.

Quelle: Sciencedaily

Protecting the ozone layer is delivering vast health benefits

An international agreement to protect the ozone layer is expected to prevent 443 million cases of skin cancer and 63 million cataract cases for people born in the United States through the end of this century, according to new research. The research team developed a computer modeling approach that revealed the effect of the Montreal Protocol and subsequent amendments on stratospheric ozone, the associated reductions in ultraviolet radiation, and the resulting health benefits.

Quelle: Sciencedaily

Cancer costs US more than $156 billion annually, with drugs a leading expense

Care for the 15 most prevalent types of cancer in the U.S. cost approximately $156.2 billion in 2018, according to a team researchers. The team also found that medication was the biggest expense and that medication expense for breast, lung, lymphoma and colorectal cancers incurred the most costs.

Quelle: Sciencedaily

Weighing cancer cells to personalize drug choices

Researchers have developed a new way to determine whether individual patients will respond to a specific cancer drug or not. This kind of test could help doctors to choose alternative therapies for patients who don’t respond to the therapies normally used to treat their cancer.

Quelle: Sciencedaily

Cancer chemotherapy drug reverses Alzheimer’s symptoms in mice

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer’s disease, new research has found. The drug, Axitinib, inhibits growth of new blood vessels in the brain — a feature shared by both cancer tumors and Alzheimer’s disease. This hallmark represents a new target for Alzheimer’s therapies. Mice that underwent the therapy not only exhibited a reduction in blood vessels and other Alzheimer’s markers in their brains, they also performed remarkably well in tests designed to measure learning and memory.

Quelle: Sciencedaily

A protein causes higher risk of severe cancer progression for men

A remarkable number of life-threatening diseases manifest more severely in males than in females. One current example is COVID-19 caused by SARS CoV-2. Another example is the significantly higher risk of severe cancer progression for men. A research team at the Technical University of Munich (TUM) has now discovered a molecular cause for this difference between sexes.

Quelle: IDW Informationsdienst Wissenschaft

Intensive Begleitung bei Rückkehr in den Beruf

Von einer Krebserkrankung Betroffene könnten bei der Rückkehr in die Erwerbstätigkeit künftig von Berufslots*innen in der ambulanten Krebsberatung begleitet werden. In den nächsten drei Jahren soll eine Studie dazu beitragen, ein entsprechendes Programm zu entwickeln und die Akzeptanz, Machbarkeit und die Implementierungsbedingungen dieses Angebots zu untersuchen. Die CARES-Studie (Cancer rehabilitation support by cancer counseling centers) startet zum 1. Oktober. Sie wird durch die Deutsche Rentenversicherung Bund mit 1,6 Millionen Euro finanziert.

Quelle: IDW Informationsdienst Wissenschaft

Powerful technique details brain tumors’ formidable resiliency

A team led by researchers  has profiled in unprecedented detail thousands of individual cells sampled from patients‘ brain tumors. The findings, along with the methods developed to obtain those findings, represent a significant advance in cancer research, and ultimately may lead to better ways of detecting, monitoring and treating cancers.

Quelle: Sciencedaily

Most cases of never-smokers’ lung cancer treatable with mutation-targeting drugs

Despite smoking’s well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called ’never-smokers,‘ a study suggests that 78% to 92% of lung cancers in patients who have never smoked can be treated with precision drugs already approved by the Food and Drug Administration to target specific mutations in a patient’s tumor.

Quelle: Sciencedaily

Looking beyond DNA to see cancer with new clarity

Researchers have mapped out how hundreds of mutations involved in two types of cancer affect the activity of proteins that are the ultimate actors behind the disease. The work points the way to identifying new precision treatments that may avoid the side effects common with much current chemotherapy.

Quelle: Sciencedaily