JUNGES KREBSPORTAL – Erweiterung 
um Minxli-Videosprechstunden und 
das Thema „Bewegung & Sport bei Krebs“

Berlin, 15. September 2021– Die Deutsche Stiftung für junge Erwachsene mit Krebs baut ihre digitalen Hilfsangebote weiter aus. In der individuellen Beratung im JUNGEN KREBSPORTAL sind zukünftig auch Videosprechstunden über die von der Kassenärztlichen Bundesvereinigung (KBV) zertifizierte Minxli-Lösung möglich. Gleichzeitig werden ab sofort auch Beratungen zum Thema „Bewegung & Sport bei Krebs“ angeboten.

Quelle: IDW Informationsdienst Wissenschaft

A possible new pathway for treating epileptic seizures in patients with autism

Researchers have discovered that in Nav1.2 deficient neurons, the expressions of many potassium channels are surprisingly reduced. The Nav1.2 deficiency itself doesn’t cause seizures; the issue arises when the potassium channels over-compensate for the sodium channels’ deficiency by shutting down too many potassium channels, making the neuron hyperexcitable, which causes seizures.

Quelle: Sciencedaily

Long-term benefit of SABR for operable early-stage NSCLC shown in new study

A new study showed that stereotactic ablative radiotherapy (SABR) was as effective as surgery at providing long-term benefits to patients with operable early-stage non-small cell lung cancer (NSCLC) and generated minimal side effects. The study is the first of its kind to compare long-term results of SABR against surgical treatment in patients with operable early-stage NSCLC.

Quelle: Sciencedaily

Engineers grow pancreatic ‘organoids’ that mimic the real thing

Engineers developed a way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells. Their models could help researchers develop and test potential drugs for pancreatic cancer.

Quelle: Sciencedaily

Free radicals linked to heart damage caused by cancer

A new study in animal models shows that the presence of a cancer tumor alone can lead to cardiac damage, and suggests the culprits are molecules called free radicals interacting with specific cells in the heart. Adding specific types of antioxidants to food consumed by fruit flies with tumors reversed the damage to their hearts — a finding suggesting that harm caused by free radicals was the likely link between cancer and cardiac dysfunction.

Quelle: Sciencedaily

Terroranschläge vom 11. September: Die kranken Helden

Wo die Twin Towers standen, blieb nur noch Schutt und Rauch zurück. In diesen giftigen Dämpfen arbeiteten Rettungskräfte monatelang - meist ohne Atemschutz.

Monatelang kämpften sich Rettungskräfte nach dem 11. September durch den Schutt, der vom World Trade Center übrig geblieben war. Das hat viele krank gemacht – der Staub war giftig, Tausende leiden an Krebs oder Lungenerkrankungen. Doch die kranken Helden wurden lange ignoriert.

Quelle: FAZ.NET

Newly developed software unveils relationships between RNA modifications and cancers

Researchers have developed a software called ModTect that can help reveal the relationships between RNA modifications and the development of diseases and disorders. Their work highlights the potential of using RNA modifications as biomarkers to test for diseases.

Quelle: Sciencedaily

New research shows a link between cell identities and childhood cancer type neuroblastoma

Neuroblastoma is a type of childhood cancer that develops in infants and young children. Whilst it is a relatively rare form of cancer, it is still responsible for approximately 15 percent of all cancer deaths in children. Researchers have discovered that low-risk and high-risk neuroblastoma have different cell identities, which can affect the survival rate.

Quelle: Sciencedaily

Chemotherapy drug puts young children with cancer at high risk of hearing loss

A chemotherapy drug known to cause hearing loss in children is more likely to do so the earlier in life children receive it, new UBC research has found. Cisplatin is a life-saving treatment for many children with cancer, but the study shows that the hearing of very young children is impacted early during treatment and is affected to a greater extent than that of older children.

Quelle: Sciencedaily

Four independent studies show rovalpituzumab tesirine ineffective against small cell lung cancer

Four independent studies demonstrate that rovalpituzumab tesirine for small-cell lung cancer (SCLC) is not effective against SCLC, casting a pall over the future of the therapy and closing a door that seemed opened four years ago when the first study on the therapy was published.

Quelle: Sciencedaily

Study illuminates origins of lung cancer in never smokers

A genomic analysis of lung cancer in people with no history of smoking has found that a majority of these tumors arise from the accumulation of mutations caused by natural processes in the body. This study describes three molecular subtypes of lung cancer in people who have never smoked. These insights will help unlock the mystery of how lung cancer arises in people who have no history of smoking and may guide the development of more precise clinical treatments.

Quelle: Sciencedaily

Metabolic changes in plasma and immune cells associated with COVID-19 severity, can predict patient survival

After examining the blood samples from nearly 200 COVID-19 patients, researchers have uncovered underlying metabolic changes that regulate how immune cells react to the disease. These changes are associated with disease severity and could be used to predict patient survival.

Quelle: Sciencedaily

Neue chemische Werkzeuge für die Wirkstoffentwicklung

Die Proteinkinase Akt spielt eine zentrale Rolle bei der Entstehung von Krebs. Die unterschiedlichen Funktionen ihrer drei Isoformen sind jedoch bis heute nicht geklärt. Das liegt vor allem daran, dass geeignete biochemische und zelluläre Aufklärungsstrategien fehlen. Die Arbeitsgruppe um Prof. Daniel Rauh von der TU Dortmund hat nun neue chemische Werkzeuge entwickelt, die das Verständnis der Akt-Isoform-spezifischen Funktionen in Gesundheit und Krankheit verbessern und die Entwicklung von Therapeutika der nächsten Generation fördern können. Die Ergebnisse wurden kürzlich in der renommierten Fachzeitschrift Nature Communications veröffentlicht.

Quelle: IDW Informationsdienst Wissenschaft

HPV vaccination will reduce throat and mouth cancers, but overall impact will take 25-plus years to see

Vaccinations against human papillomavirus (HPV), a major cause of throat and back of mouth cancers, are expected to yield significant reductions in the rates of these cancers in the U.S., but will not do so until after 2045, according to a new modeling study.

Quelle: Sciencedaily

Stem-like T cells could aid immunotherapy in cancer treatment

Researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.

Quelle: Sciencedaily

Immunotherapy for HPV+ head and neck cancer: Awakening the force within

The immune cells that are the major targets of immune checkpoint inhibitors (stem-like PD-1+ CD8 T cells) are present in HPV+ tumors from head and neck cancer patients, according to a new study. The results have implications for how immunotherapy could be used to treat this type of head and neck cancer.

Quelle: Sciencedaily

Liquid biopsies may aid diagnosis, treatment of bladder, nerve tumors

Two recent studies describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors. Despite the differences between these cancers and their associated biopsies, the studies demonstrate the possible benefits of this relatively new tool in the fight against cancer.

Quelle: Sciencedaily

Antibiotics linked to increased risk of colon cancer

There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to ten years. This has been confirmed after a study of 40,000 cancer cases. The impact of antibiotics on the intestinal microbiome is thought to lie behind the increased risk of cancer.

Quelle: Sciencedaily

In a common genetic disorder, blood test reveals when benign tumors turn cancerous

Researchers have developed a blood test that, they believe, could one day offer a highly sensitive and inexpensive approach to detect cancer early in people with NF1. The blood test could also help doctors monitor how well patients are responding to treatment for their cancer.

Quelle: Sciencedaily

Fighting brain cancer at its root

Researchers identify proteins that drive cancer stem cells. Targeting and suppressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.

Quelle: Sciencedaily

Kombinierte Tumorimpfung verstärkt krebsabtötende Immuneffekte

Wirkmechanismus der Mischimpfung gegen Krebs aufgedeckt: Die Kombination zweier Impfstoffe ist nicht nur gegen COVID-19 vielversprechend – sondern auch bei Krebs. In einer gemeinsamen Studie mit der Med-Uni Wien und Biotech-Partnern aus der pharmazeutischen Industrie ist es einem Team um den Krebsexperten Guido Wollmann von der Medizinischen Universität Innsbruck gelungen, die Vorteile der heterologen Tumorimpfung zu beleuchten.

Quelle: IDW Informationsdienst Wissenschaft

Granulocytes may weaken immune response in connection with COVID-19

Information on granulocytes sheds light on the mechanisms associated with COVID-19 and other infectious diseases.

Quelle: Sciencedaily

Kampf gegen Krebs: EU führt neue Grenzwerte für Blei in Lebensmitteln ein

Blei schadet – und das schon in geringsten Mengen: In der EU gelten ab sofort neue Grenzwerte für das Schwermetall in vielen Lebensmitteln. Sie sollen vor allem Kleinkinder, aber auch Erwachsene schützen.

Quelle: SPIEGEL ONLINE

COVID-19 in children with cancer: Severe disease and disrupted treatment

Scientists from St. Jude Children’s Research Hospital and the International Society of Paediatric Oncology report results from the Global Registry of COVID-19 and Childhood Cancer.

Quelle: Sciencedaily

The risk of developing a disease linked to genetics tends to decrease with age

People often get sicker as they grow older, but new research finds that the impact of a person’s genes on their risk of getting sick actually wanes with age.

Quelle: Sciencedaily